Fibronectin Mouse, Unlabeled, Clone: 10, BD

Mouse Monoclonal Antibody

Codice del prodotto	Marca	Quantity
15805249	BD Biosciences 610077	50 μg
15815249	BD Biosciences 610078	150 μg

Descrizione

The 240kDa dimeric fibronectin protein exists in two forms: a soluble protomer in body fluids and an insoluble multimer in the extracellular matrix. The latter is the primary functional form and creates a substrate for cell migration, a role which makes fibronectin vital to embryogenesis and wound response. Fibronectin mediates cytoskeletal organization, cell attachment, and cellular signaling through interactions with cellular receptors. Although various isoforms of fibronectin are derived by alternative splicing, they share a common N-terminus which is a critical region for cell surface binding in an initial step of multimer assembly. Further polymerization steps are regulated by fibronectin/integrin interactions and result in generation of the complex fibrils that constitute the fibronectin matrix.

Host Species: Mouse
Clone: 10
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Fibronectin
Formula Weight [Chemical]: 240kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifica

• Antigen: Fibronectin
• Concentration: 250μg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Biology
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: FN; LETS

• Clone: 10
• Applications: Flow Cytometry
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Bovine, Canine, Chicken, Human, Mouse, Rat
• Immunogen: Human Fibronectin
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

For Research Use Only.