Fibrinogen Polyclonal Antibody, Invitrogen™

Goat Polyclonal Antibody

Brand:  Invitrogen PA126809

Product Code. 11591762

Description

PA1-26809 detects fibrinogen from human samples. PA1-26809 has been successfully used in IHC (P) and Western blot procedures. The PA1-26809 immunogen is fibrinogen from human plasma. Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20° C or below, avoiding multiple freeze-thaw cycles.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

Specifications

• Antigen: Fibrinogen
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGG
• Gene Alias: 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Goat
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 90 mg/mL
• Formulation: whole serum diluted in 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: P02671, P02675, P02679
• Gene Symbols: FGA, FGB, FGG
• Immunogen: Fibrinogen from human plasma.
• Regulatory Status: RUO
• Gene ID (Entrez): 2243, 2244, 2266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid