Fibrinogen Monoclonal Antibody (27C8), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA120039

Product Code. 11533683

Description

MA1-20039 detects fibrinogen in human samples.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

Specifications

• Antigen: Fibrinogen
• Classification: Monoclonal
• Concentration: 4.3 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P02671, P02675, P02679
• Gene Symbols: FGA, FGB, FGG
• Immunogen: Fibrin degradation products.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Western Blot
• Clone: 27C8
• Conjugate: Unconjugated
• Gene: FGA
• Gene Alias: 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2243, 2244, 2266
• Content And Storage: 4° C, do not freeze
• Form: Liquid