missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody, HRP, Invitrogen™
Goat Polyclonal Antibody
Brand: Invitrogen PA17498
This item is not returnable.
View return policy
Description
The PA1-7498 antibody reacts with Epstein-Barr virus EBNA-1. PA1-7498 has been successfully used in ELISA applications. The PA1-7498 antibody was raised against Recombinant EBV EBNA-1. Note: Sodium azide is a potent inhibitor of peroxidase.
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.Specifications
Epstein Barr Virus Nuclear Antigen 1 | |
Polyclonal | |
HRP | |
EBNA-1 | |
Purified recombinant EBV EBNA-1. | |
1 mL | |
Primary | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Immunohistochemistry, Western Blot | |
1-2 mg/mL | |
PBS with 10mg/mL BSA and 0.002% thimerosal | |
Goat | |
IgG fraction | |
RUO | |
Virus | |
Antibody | |
IgG |