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Endothelin Receptor A Polyclonal Antibody, Invitrogen™

Endothelin Receptor A Antibody, PA3-065, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: ICC, IF, IHC (Frozen), IHC (Paraffin), WB.

Brand:  Invitrogen PA3065

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11375723

  • £311.00 / 100µL


Estimated Shipment
07-12-2017
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Description

Description

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: COOH-terminal amino acids of mouse ETA (408-427) KNQEQNNHNTERSSHKDSMN coupled to KLH
Formulation: 100μL unpurified antibody in whole serum and 0.02% sodium azide
Synonyms: ET-A, G-protein coupled receptor 10, endothelin A receptor, endothelin-1 receptor
Uniprot Accession: P25101, P26684, Q61614
Entrez GeneID: 13617, 1909, 24326
Gene Symbol: EDNRA
PA3-065 detects Endothelin Receptor A from human, mouse, and rat samples. PA3-065 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By western blot, this antibody detects a 46kDa protein corresponding to mouse Endothelin Receptor A.
References:
Test: IHC (P), Species: Hu, Reference: Reassessment of endothelin receptor A expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-8. (Apr 2015) Peptides, Vol: 66, , 19-25, Lupp A,Mann A,Heeb A,Kaemmerer D,Sänger J,Evert M,Evert K,Mawrin C,Schulz S; Pubmed ID: 25708416
Specifications

Specifications

Endothelin Receptor A
Unconjugated
P25101, P26684, Q61614
ET-A, G-protein coupled receptor 10, endothelin A receptor, endothelin-1 receptor
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Rat
Western Blot
100μL unpurified antibody in whole serum and 0.02% sodium azide
Serum
EDNRA
COOH-terminal amino acids of mouse ETA (408-427) KNQEQNNHNTERSSHKDSMN coupled to KLH
100μL
Primary
13617, 1909, 24326
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