ELK Rec. Tyrosine Kinase Polyclonal Antibody, Invitrogen™
ELK Rec. Tyrosine Kinase Antibody, PA1-12411, from Invitrogen™. Species Reactivity: Human; Applications: Immunoprecipitation.
Brand: Invitrogen PA112411
Code : LD
Additional Details : Weight : 0.01000kg
DescriptionephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.
Host Species: Sheep
Cross Reactivity: Human
Immunogen: Recombinant protein corresponding to residues 586-984 of C terminus of human ephB1.
Formulation: 250μg purified antibody in PBS and 0.08% sodium azide
Synonyms: ELK, EPHT2, FLJ37986, Hek6, NET
Uniprot Accession: P54762
Entrez GeneID: 2047
Gene Symbol: EPHB1
A suggested positive control for this product is human brain lysate.
|ELK Rec. Tyrosine Kinase|
|ELK, EPHT2, FLJ37986, Hek6, NET|
|Avoid Freeze/Thaw Cycles|
|250μg purified antibody in PBS and 0.08% sodium azide|
|Recombinant protein corresponding to residues 586-984 of C terminus of human ephB1.|