EGF Receptor Mouse anti-Human, Brilliant Violet 510, Clone: EGFR.1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 563344

Product Code. 15882709

Description

The EGFR.1 monoclonal antibody specifically binds to the epidermal growth factor receptor (EGF-R). The EGF-R is a transmembrane glycoprotein ofapproximately 170 kDa that is expressed on most cells. It consists of a glycosylated extracellular domain which binds to epidermal growth factor (EGF), a transmembrane domain, and an intracellular domain with tyrosine-kinase activity essential for signal transduction. The EGF-R plays an important role in the growth and differentiation of many cellular types. Transforming growth factor α (TGFα), vaccinia virus growth factor, and related growth factors can also bind to and signal through the EGF-R.

Specifications

• Antigen: EGF Receptor
• Classification: Monoclonal
• Conjugate: Brilliant Violet 510
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: EGFR.1
• Description: EGFR; ERBB; ERBB1; HER1; mENA; PIG61
• Host Species: Mouse
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.