DNA-PKcs Monoclonal Antibody, Clone: 18-2 + 25-4 + 42-psc, Invitrogen™

DNA-PKcs Antibody (18-2 + 25-4 + 42-psc), MA5-13404, from Invitrogen™. Species Reactivity: Ck, Hm, Hu, Ms, Xnl; Applications:GS, IF, IHC (P), IP, WB.

Brand:  Invitrogen MA513404

Product Code. 11324843

Description

DNA-PKcs Antibody (18-2 + 25-4 + 42-psc), MA5-13404, from Invitrogen. Species Reactivity: Chicken, Hamster, Human, Mouse, Xenopus laevis; Applications: Gel Shift, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot.

DNA-dependent Protein Kinase (DNA-PKcs) phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. In vivo, it is involved in repairing double strand DNA breaks
Host Species: Mouse
Cross Reactivity: Chicken, Hamster, Human, Mouse, Xenopus laevis
Isotype: IgG1/IgG2a
Clone: 18-2 + 25-4 + 42-psc
Immunogen: Human DNA-dependent Protein Kinase purified from HeLa cells
Formulation: 500μL purified antibody (0.2mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Synonyms: DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460
Uniprot Accession: P78527, P97313, Q8QGX4, Q9DEI1
Entrez GeneID: 100770748, 19090, 373602, 395376, 5591
Gene Symbol: PRKDC
MA5-13404 targets DNA-PKcs in gel shift, immunofluorescence, immunohistochemistry (paraffin), immunoprecipitation, and western blot applications and shows reactivity with Chicken, Hamster, Human, mouse, and Xenopus laevis samples. The MA5-13404 immunogen is human DNA-dependent Protein Kinase purified from HeLa cells.
References:
Test: ICC, Species: Hu, Reference: Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites. (2002 Nov) Mol Cell Biol, Vol: 22, 22, 8088-99, Mo X, Dynan WS; Pubmed ID: 12391174

Specifications

• Antigen: DNA-PKcs
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: P78527, P97313, Q8QGX4, Q9DEI1
• Gene Symbols: PRKDC
• Immunogen: Human DNA-dependent Protein Kinase purified from HeLa cells
• Regulatory Status: RUO
• Gene ID (Entrez): 100770748, 19090, 373602, 395376, 5591
• Content And Storage: Store at 4°C
• Isotype: IgG1, IgG2a

• Applications: Gel Shift, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 18-2 + 25-4 + 42-psc
• Formulation: 500μL purified antibody (0.2mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Alias: DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Chicken, Hamster, Human, Mouse, X. laevis
• Form: Purified