DIO3 Rabbit anti-Hamster, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA522886

Product Code. 13288038

Description

The target sequence has 93% sequence homology with hamster. Suggested positive control: rat placenta tissue lysate.

Dio3, or type 3 iodothyronine deiodinase, can regulate circulating fetal thyroid hormone concentrations throughout gestation. It has an essential role for regulation of thyroid hormone inactivation during embryological development, and may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Dio3 has been linked to the development of consumptive hypothyroidism in both infants and adults.

Specifications

• Antigen: DIO3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P55073, Q91ZI8, P49897
• Gene Symbols: DIO3
• Immunogen: Synthetic peptide made to an internal portion of the rat protein (within residues 1-100).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Hamster, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Gene: DIO3
• Gene Alias: 5DIII, D3, DIOIII, TXDI3, iodothyronine deiodinase, placental type, thyroxine deiodinase type III (selenoprotein), type 3 DI, type 3 iodothyronine selenodeiodinase, type III iodothyronine deiodinase, type-III 5′ deiodinase, type-III 5′-deiodinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100753739, 107585, 1735, 29475
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid