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DAP12 Polyclonal Antibody, Invitrogen™

DAP12 Antibody, PA1-12701, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Brand:  Invitrogen PA112701

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11586072

  • £317.00 / 100µg


Estimated Shipment
22-01-2018
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Description

Description

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Recombinant DAP12 protein.
Formulation: 100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Synonyms: TYROBP, KARAP, PLOSL
Uniprot Accession: O43914, O54885
Entrez GeneID: 22177, 7305
Gene Symbol: TYROBP
A suggested positive control for this product is NKp44 positive cells.
Specifications

Specifications

DAP12
Unconjugated
O43914, O54885
TYROBP, KARAP, PLOSL
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Murine
Western Blot
100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Purified
TYROBP
Recombinant DAP12 protein.
100μg
Primary
22177, 7305
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