DAP12 Polyclonal Antibody, Invitrogen™

DAP12 Antibody, PA1-12701, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-12701

DAP12

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11586072

Quantity Price
1 £ 317.0 / 100µg
Estimated Shipment date
from Supplier 11-01-2017
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Description and Specification

Specification

Antigen DAP12
Applications Immunoprecipitation
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Gene Accession No. O43914, O54885
Gene Alias TYROBP, KARAP, PLOSL
Gene Symbols TYROBP
Host Species Rabbit
Immunogen Recombinant DAP12 protein.
Isotype IgG
Quantity 100μg
Species Reactivity Human, Mouse
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 22177, 7305

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Recombinant DAP12 protein.
Formulation: 100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Synonyms: TYROBP, KARAP, PLOSL
Uniprot Accession: O43914, O54885
Entrez GeneID: 22177, 7305
Gene Symbol: TYROBP
A suggested positive control for this product is NKp44 positive cells.