CXCR5 Rat anti-Human, Biotin, Clone: RF8B2, BD

Rat Monoclonal Antibody

Brand:  BD Biosciences 552118

Product Code. 15896758

Description

The monoclonal antibody RF8B2 reacts with the human CXC chemokine receptor, CXCR5. CXCR5 (aka BLR-1 NLR and MDR15), a seven transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokine, CXCL13/BLC/BCA-1. In peripheral blood, CXCR5 expression is restricted to B lymphocytes and a small subset of CD4+ and CD8+ lymphocytes. The restricted expression pattern of CXCR5 on B cells suggested that this receptor might function as a regulator of B cell migration. Stimulation of T cells with anti-CD3 monoclonal antibody lead to the down-regulation of CXCR5. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Rat
Clone: RF8B2
Isotype: IgG2b κ
Species Reactivity: Human
Immunogen: Human CXCR5 Transfected Cell Line

Flow Cytometry, Immunofluorescence

Specifications

• Antigen: CXCR5
• Classification: Monoclonal
• Conjugate: Biotin
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Immunogen: Human CXCR5 Transfected Cell Line
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: RF8B2
• Description: CD185; Chemokine C-X-C motif receptor 5; BLR1; MDR-15
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.