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CCCTC-binding factor (zinc finger protein), Mouse, Polyclonal Antibody, Abnova™

Product Code. 16192996
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Quantity:
50 μL
Unit Size:
50µL
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16192996 50 μL 50µL
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Product Code. 16192996 Supplier Abnova Supplier No. H00010664A01.50uL

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Description

Mouse polyclonal antibody raised against a partial recombinant CTCF.

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq]

Sequence: MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQV

Specifications

Antigen CCCTC-binding factor (zinc finger protein)
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant CTCF.
Formulation 50% glycerol
Gene CTCF
Gene Accession No. BC014267
Gene Symbols CTCF
Host Species Mouse
Immunogen CTCF (AAH14267, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Research Discipline Cell Cycle
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 10664
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Serum
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