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Invitrogen™ CPEB1 Polyclonal Antibody

Product Code. 11545922
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Quantity:
100 μg
Unit Size:
100µg
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11545922 100 μg 100µg
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Product Code. 11545922 Supplier Invitrogen™ Supplier No. PA11100

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Description

Rabbit Polyclonal Antibody

PA1-1100 detects recombinant mouse and rat CPEB (cytoplasmic polyadenylation element binding protein). PA1-1100 has been successfully used in Western blot, ICC/IF and IHC-P procedures. By Western blot, this antibody detects ~62 and kDa protein representing recombinant mouse CPEB. The PA1-1100 immunogen is a synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB. This sequence is completely conserved in mouse. The PA1-1100 immunizing peptide (Cat. # PEP-171) is available for use in neutralization and control experiments.

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CPEB1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene CPEB1
Gene Accession No. P0C279, P70166, Q9BZB8
Gene Alias AU024112; CEBP; Cpeb; CPEB1; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element binding protein 1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; mCPEB; mCPEB-1; MGC34136; MGC60106
Gene Symbols CPEB1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues C H(545) S M E G L R H H S P L M R N Q K N(562) of human CPEB.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12877, 293056, 64506
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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