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Invitrogen™ CNTF Polyclonal Antibody
Description
Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for an additional stability.
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Specifications
Specifications
| Antigen | CNTF |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Whole serum with no preservative |
| Gene | CNTF |
| Gene Accession No. | P20294, P26441, P51642 |
| Gene Alias | AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF |
| Gene Symbols | CNTF |
| Show More |
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