CETP Polyclonal Antibody, Invitrogen™
CETP Antibody, PA1-050, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot.
Brand: Invitrogen PA1050
Code : LE
Additional Details : Weight : 0.01000kg
DescriptionIt has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to specifically accelerate the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. In general, elevated levels of CETP have been associated with increased risk of coronary heart disease.
Host Species: Rabbit
Cross Reactivity: Human
Immunogen: Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.
Formulation: 100μg purified antibody (1mg/mL) in PBS with 1mg/mL BSA and 0.05% sodium azide
Synonyms: Cholesteryl Ester Transfer Protein, Lipid transfer protein I
Uniprot Accession: P11597
Entrez GeneID: 1071
Gene Symbol: CETP
PA1-050 detects cholesteryl ester transfer protein (CETP) from human tissues. PA1-050 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ∽70 kDa band from human liver extracts representing CETP. The PA1-050 immunogen is a synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.This peptide (Cat. # PEP-209) is available for use in neutralization and control experiments.
|Cholesteryl Ester Transfer Protein, Lipid transfer protein I|
|Avoid Freeze/Thaw Cycles|
|100μg purified antibody (1mg/mL) in PBS with 1mg/mL BSA and 0.05% sodium azide|
|Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.|