Invitrogen™ CENPF Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA116826

Product Code. 11595393

Description

Suggested positive control: HeLa and SK-N-SH cells.

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitosis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Specifications

• Antigen: CENPF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CENPF
• Gene Alias: 6530404A22Rik; AH antigen; AI325968; cell-cycle-dependent 350K nuclear protein; CENF; CENPF; CENP-F; CENP-F kinetochore protein; centromere autoantigen F; centromere protein F; centromere protein F, (mitosin); centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; im:7140452; im:7144238; im:7154719; im:7156761; kinetochore protein CENPF; Lek1; leucine, glutamic acid, lysine family 1 protein; mitosin; PRO1779; RP11-262H5.1; si:ch211-152h14.2; STROMS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100050180, 1063, 108000, 533089
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P49454
• Gene Symbols: CENPF
• Immunogen: A bacterial fusion protein from the C-terminus of human CENPF.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Bovine, Horse
• Product Type: Antibody
• Isotype: IgG