CENPF Polyclonal Antibody, Invitrogen™

CENPF Antibody, PA1-16826, from Invitrogen™. Species Reactivity: Bovine, Human; Applications: FACS, ICC, IF, IP, WB.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-16826

CENPF

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11595393

Quantity Price
1 £ 257.0 / 50µL
Estimated Shipment date
from Supplier 17-03-2017
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Description and Specification

Specification

Formulation 50μL purified antibody (2.5mg/mL) in PBS with 50% glycerol and 0.05% sodium azide
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blot
Gene ID (Entrez) 1063
Cross Reactivity Bovine
Cross Reactivity Human
Antigen CENPF
Storage Requirements Avoid Freeze/Thaw Cycles
Immunogen A bacterial fusion protein from the C-terminus of CENP-F.
Isotype IgG
Primary or Secondary Primary
Format Purified
Gene Accession No. P49454
Host Species Rabbit
Conjugate Unlabeled
Species Reactivity Bovine, Human
Gene Alias AH Antigen, CENF, CENP F Kinetochore Protein, Centromere Protein F, Mitosin, CENPF
Gene Symbols CENPF
Quantity 50μL
Monoclonal or Polyclonal Polyclonal

The kinetophore is a macromolecular structure that is associated with the centromeres of chromosomes and is responsible for establishing and maintaining the connections with the microtubules of the mitotic spindle. The proteins that reside within the chromosomal domain fall into two broad classes: those that associate with the centromere throughout the cell cycle and those that are found at the centromere in a cell cycle specific manner. Members of the first class include CENP-A, CENP-B, and CENP-C. The members of the second class include several ubiquitous cellular proteins such as calmodulin, tubulin, dynein and p34 cdc2 and also CENP-E and CENP-F. CENP-F appears to be the earliest member to interact with the centromere-kinetochore complex. CENP-F also shows a cell-cycle distribution that is both temporally regulated and diverse in terms of the structural components it localizes to and therefore may play a role in several mitotic events.
Host Species: Rabbit
Cross Reactivity: Bovine, Human
Isotype: IgG
Immunogen: A bacterial fusion protein from the C-terminus of CENP-F.
Formulation: 50μL purified antibody (2.5mg/mL) in PBS with 50% glycerol and 0.05% sodium azide
Synonyms: AH Antigen, CENF, CENP F Kinetochore Protein, Centromere Protein F, Mitosin, CENPF
Uniprot Accession: P49454
Entrez GeneID: 1063
Gene Symbol: CENPF
Suggested positive control: HeLa and SK-N-SH cells.