CDw210 Rat anti-Human, Unlabeled, Clone: 3F9, BD

Rat Monoclonal Antibody

Brand:  BD Biosciences 556012

Product Code. 15818588

Description

Reaacts with 90-110kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNγR (CDw119), IFNα/βR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages. Clone 3F9 is specific for human IL-10R and its binding to the receptor can be blocked by recombinant human IL-10 (rhIL-10). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CDw210
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: IL-10 receptor
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: 3F9
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human IL-10R alpha Recombinant Protein
• Quantity: 0.1 mg
• Research Discipline: Cell Biology
• Target Species: Human
• Isotype: IgG2a κ

For Research Use Only.