CD80 Mouse anti-Rat, PE, Clone: 3H5, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 555014

Product Code. 15837958

Description

The 3H5 antibody reacts with CD80 (B7-1), a member of the Ig superfamily of transmembrane proteins. CD80, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD80 is predominantly expressed on antigen-presenting cells. It can be induced on splenic B cells by in vitro polyclonal activation such as LPS treatment. 3H5 mAb is reported to block the costimulatory function of rat CD80 and to immunoprecipitate CD80 from Lewis-S1 cell lysates.

Flow Cytometry

Specifications

• Antigen: CD80
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: B7-1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 3H5
• Conjugate: PE
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Rat HTLV-1-transformed T-cell line Lewis-S1
• Quantity: 0.2 mg
• Research Discipline: Immunology
• Target Species: Rat
• Isotype: IgG1 κ

For Research Use Only.