CD80 Mouse anti-Human, PE, Clone: L307.4, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 340294

Product Code. 15825858

Description

Reacts with B7/BB1, a 60kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.

Specifications

• Antigen: CD80
• Classification: Monoclonal
• Concentration: 3.2μg/mL
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Immunogen: Human B7-transfected L cells
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

• Applications: Flow Cytometry
• Clone: L307.4
• Conjugate: PE
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.