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CD62P Mouse anti-Human, FITC, Clone: AC1.2, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 550866

Product Code. 15896408

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Description

Description

Reacts with the human form of the 140 kDa membrane glycoprotein, P-selectin, formerly known as platelet activation-dependent granule external membrane protein (PADGEM), or granule membrane protein (GMP-140). P-selectin is stored in the α -granules of platelets and the Weibel-Palade bodies of endothelial cells, and is rapidly transported to the plasma membrane upon activation. P-selectin is thought to mediate the initial adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses, and of activated platelets to neutrophils and monocytes in hemostasis. This antibody is a non-blocking monoclonal antibody and is suitable for immunohistochemical staining of formalin-fixed, paraffin embedded, tissue sections. Clone AC1.2 also cross reacts with activated platelets of baboon, and both rhesus and cynomolgus macaque monkeys. The reactivity on resting and activated platelets is similar to that observed on resting and activated platelets of human donors.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD62P
Monoclonal
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
AC1.2
P-Selectin
Mouse
50 Tests
Immunology
Baboon, Cynomolgus, Rhesus Monkey
IgG1 κ
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