CD50 (ICAM-3) Mouse anti-Human, FITC, Clone: TÜ41, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 555958

Product Code. 15828558

Description

The TU41 monoclonal antibody specifically binds to the intracellular adhesion molecule-3 (ICAM-3) which is also known as CD50. ICAM-3 is a 110-120 kDa type I membrane glycoprotein expressed on all leukocytes (platelets and erythrocytes are ICAM-3-negative). ICAM-3 is also expressed on epidermal Langerhans cells and endothelial cells. It predominantly interacts with LFA-1 (CD11a/CD18) without requiring activation as the initial dendritic cell-T lymphocyte interaction. ICAM-3 is an important LFA-1 ligand that functions in the initiation of the immune/inflammatory response and also plays a role in chemotaxis.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CD50
• Classification: Monoclonal
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: TÜ41
• Description: ICAM-3; ICAM3; Intercellular adhesion molecule 3
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG2b κ

For Research Use Only.