CD49e Rat anti-Mouse, Unlabeled, Clone: 5H10-27, BD

Rat Monoclonal Antibody

Brand:  BD Biosciences 553319

Product Code. 15827148

Description

The 5H10-27 (MFR5) antibody reacts with the α; 5 chain of the integrin α;5 β; 1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5–mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3e antibody.

Specifications

• Antigen: CD49e
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Integrin α5 chain
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: 5H10-27
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse mast cell line MC/9
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

For Research Use Only.