CD46, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA529672

Product Code. 13423897

Description

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene.

PA5-29672 targets CD46 in IF and WB applications and shows reactivity with Human samples.The PA5-29672 immunogen is recombinant protein fragment corresponding to a region within amino acids 174 and 359 of Human CD46.

Specifications

• Antigen: CD46
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P15529
• Gene Symbols: CD46
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 174 and 359 of Human CD46
• Quantity: 100 μL
• Gene ID (Entrez): 4179
• Content And Storage: Store at -20°C, Avoid Freeze/Thaw Cycles
• Form: Purified

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 1mg/mL
• Gene: CD46
• Gene Alias: AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG