CD45 Mouse anti-Rat, Unlabeled, Clone: OX-1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 550566

Product Code. 15876328

Description

The OX-1 antibody reacts with all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

Specifications

• Antigen: CD45
• Classification: Monoclonal
• Concentration: 250μg/mL
• Description: Ptprc; Lca; Leucocyte common antigen; RT7; T200
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: OX-1
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
• Immunogen: Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
• Quantity: 1 mL
• Research Discipline: Immunology
• Target Species: Rat
• Isotype: IgG1 κ

For Research Use Only.