CD44/H-CAM Alexa Fluor 488 Monoclonal Antibody, Clone: MEM-85, Invitrogen™

CD44/H-CAM Antibody, Alexa Fluor 488 conjugate (MEM-85), MA5-18139, from Invitrogen™. Species Reactivity: Human; Applications: Flow Cytometry.

Overview
Brand: Invitrogen

Manufacturer Part Number: MA518139

Monoclonal Antibody,CD44/H-CAM,Alexa Fluor 488

UNSPSC: 12352203

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 15367404

Quantity Price
1 £ 254.0 / 100 tests
Estimated Shipment date
from Supplier 16-12-2016
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Description and Specification

Specification

Antigen CD44/H-CAM
Applications Flow Cytometry
Clone MEM-85
Conjugate Alexa Fluor 488
Cross Reactivity Human
Format Purified
Formulation 100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
Gene Accession No. P16070
Gene Alias CD44 antigen, Cell surface glycoprotein CD44, hyaluronate binding protein, ECMR-III, GP90 lymphocyte homing adhesion receptor, HUTCH-I, PGP-1, extracellular matrix receptor III, hermes antigen, hyaluronate receptor, phagocytic glycoprotein 1, phagocytic glycoprotein I
Gene Symbols CD44
Host Species Mouse
Immunogen Leukocytes of a patient suffering from LGL Type Leukaemia
Isotype IgG2b
Quantity 100 TS
Species Reactivity Human
Storage Requirements DO NOT FREEZE!
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 960

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG2b
Clone: MEM-85
Immunogen: Leukocytes of a patient suffering from LGL Type Leukaemia
Formulation: 100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
Synonyms: CD44 antigen, Cell surface glycoprotein CD44, hyaluronate binding protein, ECMR-III, GP90 lymphocyte homing adhesion receptor, HUTCH-I, PGP-1, extracellular matrix receptor III, hermes antigen, hyaluronate receptor, phagocytic glycoprotein 1, phagocytic glycoprotein I
Uniprot Accession: P16070
Entrez GeneID: 960
Gene Symbol: CD44
This antibody reacts with both cell surface-expressed and soluble form of CD44 antigen. It is negative on platelets and hepatocytes.