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CD44/H-CAM Alexa Fluor 488 Monoclonal Antibody, Clone: MEM-85, Invitrogen™

CD44/H-CAM Antibody, Alexa Fluor 488 conjugate (MEM-85), MA5-18139, from Invitrogen™. Species Reactivity: Human; Applications: Flow Cytometry.

Brand:  Invitrogen MA518139

UNSPSC : 12352203

Code : NEW

Additional Details : Weight : 0.01000kg

Product Code. 15367404

  • £254.00 / 100 tests


Estimated Shipment
08-09-2017
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Description

Description

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG2b
Clone: MEM-85
Immunogen: Leukocytes of a patient suffering from LGL Type Leukaemia
Formulation: 100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
Synonyms: CD44 antigen, Cell surface glycoprotein CD44, hyaluronate binding protein, ECMR-III, GP90 lymphocyte homing adhesion receptor, HUTCH-I, PGP-1, extracellular matrix receptor III, hermes antigen, hyaluronate receptor, phagocytic glycoprotein 1, phagocytic glycoprotein I
Uniprot Accession: P16070
Entrez GeneID: 960
Gene Symbol: CD44
This antibody reacts with both cell surface-expressed and soluble form of CD44 antigen. It is negative on platelets and hepatocytes.
Specifications

Specifications

CD44/H-CAM
MEM-85
100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
Purified
CD44
Leukocytes of a patient suffering from LGL Type Leukaemia
100 Tests
Primary
960
Flow Cytometry
Alexa Fluor 488
P16070
CD44 antigen, Cell surface glycoprotein CD44, hyaluronate binding protein, ECMR-III, GP90 lymphocyte homing adhesion receptor, HUTCH-I, PGP-1, extracellular matrix receptor III, hermes antigen, hyaluronate receptor, phagocytic glycoprotein 1, phagocytic glycoprotein I
Murine
IgG2b
DO NOT FREEZE!
Monoclonal
Human