CD32 Mouse anti-Human, PE, Clone: 3D3, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 552884

Product Code. 15886888

Description

Reacts with FcγRII (CD32), a 40 kDa, polymorphic transmembranous glycoprotein, highly glycosylated molecule (encoded by at least two genes), expressed on monocytes, granulocytes, platelets and B cells. Unlike FLI28.6, 3D3 mAb detected a polymorphic CD32 antigen expressed on B cells of all donors, but only on platelets, monocytes and granulocytes of some donors. The platelets from 3D3+ donors respond to certain stimulatory mAb such as CD165 (clone SN2, Cat. No. 556050) and result in aggregation. On the other hand, the platelets from 3D3 negative donors do not form aggregates after stimulation. Individuals can be divided into two groups as responder and non-responder depending on expression, or non-expression, of 3D3. In comparison to 3D3, FLI8.26 detects a monomorphic CD32 antigen expressed on all human donors.

Specifications

• Antigen: CD32
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 3D3
• Description: FcγRII
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.