CD309 (VEGFR-2) Mouse anti-Human, PE, Clone: 89106, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 560494

Product Code. 15830249

Description

The 89106 monoclonal antibody reacts with CD309 (vascular endothelial growth factor r eceptor-2 (VEGFR-2)), a receptor protein tyrosine kinase closely related to CD117 (c-kit) and CD140a (PDGF Receptor α chain) of the immunoglobulin superfamily. VEGFR-2, al so known as fetal liver kinase 1 (Flk-1) or kinase insert domain receptor (KDR), is a receptor for vascular endothelial growth factor (VEGF). It is expressed, at the mRNA and protein levels, on distinct sets of mesoderm during gastrulation and on endothelial cells in embryonic tissues. In vivo in vitro studies indicate that VEGFR-2 is required for the embryonic development of vascular endothelial and hematopoietic cells. Human cardiac progenitor cells derived from human embryonic stem cells arise from a population of cells that express VEGFR-2.

Specifications

• Antigen: CD309
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human VEGFR-2
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: 89106
• Description: FLK1; Fetal liver kinase 1; KDR; VEGFR2; VEGF Receptor 2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.