CD28 Mouse anti-Human, Unlabeled, Clone: L293, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 348040

Product Code. 15856128

Description

The CD28 antibody, clone L293, is derived from hybridization of Sp2/0-Ag14 mouse myeloma cells with spleen cells from BALB/c mice immunized with the HPB-ALL T-cell line.

The CD28 antigen, a disulfide-linked homodimeric glycoprotein, Mr 44 kilodaltons (kd), is a cell-adhesion molecule (CAM) and functions as the ligand for CD80 (B7-1) and CD86 (B7-2) antigens, which are present on activated B lymphocytes, monocytes, and dendritic cells. Interaction of the CD28 antigen with CD80 or CD86 antigens, or both, co-stimulates CD2 and CD3 antigen/T-cell antigen receptor (TCR)–dependent T-cell–mediated proliferation and cytotoxicity.

Specifications

• Antigen: CD28
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

• Applications: Flow Cytometry
• Clone: L293
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 200 μg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.