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PD-1 Monoclonal Antibody (J43), PE, Invitrogen™
Armenian Hamster Monoclonal Antibody
Brand: Invitrogen PA535011
Code : NEW
Additional Details : Weight : 0.01000kg
Description
PA5-35011 targets CD279/PD1 in FACS applications and shows reactivity with Mouse samples. The PA5-35011 immunogen is pD-1 cDNA transfectant.
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "e;danger signals"e; such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.Specifications
| PD-1 | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
| Q02242 | |
| Pdcd1 | |
| PD-1 cDNA transfectant | |
| 50 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
| Flow Cytometry | |
| J43 | |
| PE | |
| Pdcd1 | |
| CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2 | |
| Armenian Hamster | |
| Protein G | |
| RUO | |
| 18566 | |
| 4° C, do not freeze | |
| Liquid |