CD27 Mouse anti-Human, PE-CF594, Clone: M-T271, BD

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15861819	BD Biosciences 562324	25 Tests
15891789	BD Biosciences 562297	100 Tests

Description

The M-T271 monoclonal antibody specifically binds to CD27. CD27 presents asa type I transmembrane, disulphide-linked 110 kDa homodimer comprised of two polypeptide chains. The CD27 molecule is a lymphocyte-specific member of the TNF/NGF-R family, and is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes, activated B cells and NK cells. CD27 is highly induced on T cells after TCR stimulation. CD27 binds to CD70 (also known as, CD27 ligand or CD27L) and may be involved in cellular interaction of T and B lymphocytes.

This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red (eg 610/20-nm filter).

Specifications

• Antigen: CD27
• Applications: Flow Cytometry
• Conjugate: PE-CF594
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152

• Clone: M-T271
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human T-CLL cells
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.