CD249 Mouse anti-Human, PE, Clone: 2D3/APA, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 564533

Product Code. 15833709

Description

The 2D3 monoclonal antibody specifically binds to CD249. CD249 is encoded by ENPEP and is also known as Aminopeptidase A (APA/AP-A), Glutamyl aminopeptidase (EAP), and gp160. CD249 is expressed by epithelial and endothelial cells in a variety of tissues including those that comprise the proximal tubules and glomeruli of the kidneys. It is also expressed by early B-lineage cells and cell lines. CD249 belongs to the peptidase M1 family and catalyzes the release of N-terminal glutamate (and to a lesser degree, aspartate) from peptides. This ectoenzyme catalyzes the conversion of angiotensin II to angiotensin III which is important in the local regulation of blood pressure. It may also play roles in the regulation of angiogenesis and development of B cells.

Specifications

• Antigen: CD249
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human Aminopeptidase A Transfected Cell Line
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 2D3/APA
• Description: EAP, Aminopeptidase A, Glutamyl aminopeptidase, APA, AP-A, gp160, ENPEP
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ