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CD20 Mouse anti-Human, V450, Clone: L27, BD

Product Code. 12830500
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50 Tests
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12830500 50 Tests Each
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Product Code. 12830500 Supplier BD Biosciences Supplier No. 561163

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Description

Mouse Monoclonal Antibody

The L27 antibody specificially binds to CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.

The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450 nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD20
Applications Flow Cytometry
Classification Monoclonal
Clone L27
Conjugate Violet Fluor 450 (V450)
Description MS4A1; membrane-spanning 4-domains subfamily A member 1; B1; Bp35; LEU-16
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Lymphoblastoid Cell Line
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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