CD1c Mouse anti-Human, BB515, Clone: F10/21A3, BD

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15844049	BD Biosciences 565055	25 Tests
15834049	BD Biosciences 565054	100 Tests

Description

The F10/21A3 monoclonal antibody specifically binds to CD1c. The CD1 family of transmembrane glycoproteins are structurally related to the classical major histocompatibility complex (MHC) proteins. CD1c is a type I transmembrane glycoprotein that forms heterodimers with beta-2-microglobulin. CD1c presents lipids and glycolipids of self or microbial origin to T cells. CD1c is expressed by Langerhans cells, dendritic cells, monocytes, cortical thymocytes, T cells, and some B cells.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Specifications

• Antigen: CD1c
• Applications: Flow Cytometry
• Conjugate: Brilliant Blue 515 (BB515)
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: CD1; R7; M241; BDCA1

• Clone: F10/21A3
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: GM-CSF- and IL-4-activated Human Monocytes
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.