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CD19 Mouse anti-Human, BB515, Clone: HIB19, BD

Product Code. 15833659
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100 Tests
25 Tests
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15833659 25 Tests Each
15823659 100 Tests Each
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Produktkod. 15833659 Leverantör BD Biosciences Leverantörsnummer 564457

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Beskrivning

Mouse Monoclonal Antibody

The HIB19 monoclonal antibody specifically binds to the 95 kDa type I transmembrane CD19 glycoprotein. CD19 is expressed during all stages of B-cell maturation and differentiation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 is a signal transduction molecule that regulates B cell development, activation, proliferation and differentiation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks the binding of clone B43, another CD19-specific monoclonal antibody.

The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g., 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

TRUSTED_SUSTAINABILITY

Specifikationer

Antigen CD19
Applications Flow Cytometry
Classification Monoclonal
Clone HIB19
Conjugate Brilliant Blue 515 (BB515)
Description B4; B-lymphocyte antigen CD19; Leu-12
Host Species Mouse
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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