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Description
The P1H12 antibody reacts with a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, or Mel-CAM. CD146 is a member of the immunoglobulin superfamily and is expressed by angioblasts and mesenchymal stems cells and is strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also expressed by melanoma cells, intermediate trophoblasts and a subpopulation of activated T cells. The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion that is observed very early in embryogenesis.
Specifications
| CD146 | |
| Monoclonal | |
| FITC | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human Umbilical Vein Cells | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| P1H12 | |
| MCAM; MELCAM; MUC18; Gicerin; Melanoma cell adhesion molecule | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
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