CD144 Rat anti-Mouse, Unlabeled, Clone: 11D4.1, BD

Rat Monoclonal Antibody

Brand:  BD Biosciences 550548

Product Code. 15856318

Description

The 11D4.1 antibody monoclonal antibody specifically binds to mouse CD144, also known as VE-cadherin. CD144 is a type I transmembrane protein and is a member of the cadherin superfamily. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion.

Specifications

• Antigen: CD144
• Classification: Monoclonal
• Concentration: 125μg/mL
• Description: Cdh5; Cadherin-5; CADH5; VE-cadherin; Vascular endothelial cadherin; 7B4
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: 11D4.1
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
• Immunogen: Mouse VE-Cadherin-Ig Fusion Protein
• Quantity: 1 mL
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

For Research Use Only.