CD14 Mouse anti-Human, V500, Clone: M5E2, BD

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15890999	BD Biosciences 561392	25 Tests
15880999	BD Biosciences 561391	100 Tests

Description

The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.

The antibody is conjugated to BD Horizon™ V500, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser with an Ex max of 415nm and Em Max at 500 nm. BD Horizon V500 conjugates emit at a similar wavelength to Amcyan yet exhibit reduced spillover into the FITC channel. For more information on BD Horizon V500, visit bdbiosciences.com/colors.

Specifications

• Antigen: CD14
• Applications: Flow Cytometry
• Conjugate: Violet Fluor 500 (V500)
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing protein stabilizer, glycerol and ≤0.09% sodium azide.
• Isotype: IgG2a κ
• Purification Method: Affinity Purified
• Description: LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein

• Clone: M5E2
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human CD14 Protein
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.