CD137 Ligand Mouse anti-Human, PE, Clone: C65-485, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 559446

Product Code. 15829728

Description

Reacts with a type II membrane protein known as 4-1BB ligand. This molecule belongs to the TNF superfamily. It has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via 4-1BB ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human 4-1BB ligand to be expressed preferentially on primary B cells and B-cell lines. C65-485 antibody is able to react with recombinant human 4-1BB ligand (rh4-1BBL) bound to CD137 (4-1BB receptor) expressed on PHA-stimulated PBMC.

Specifications

• Antigen: CD137 Ligand
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: C65-485
• Description: 4-1BB Ligand
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ