CD120a Mouse anti-Human, Unlabeled, Clone: MABTNFR1-B1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 550514

Product Code. 15836298

Description

The TNFR1-B1 antibody reacts with the extracellular domain of CD120A which is also known as the 55 kDa receptor for the human cytokines, tumor necrosis factor (TNF) and lymphotoxin-alpha (LT- α ). This receptor is referred to as the p55 or Type I Tumor Necrosis Factor Receptor (TNFRI). TNFRI are expressed by a variety of cell lines, tumor cells, and normal cell types including T cells, monocytes, macrophages, neutrophils, endothelial cells, hepatocytes, chondrocytes, and fibroblasts. Naive B cells express very low or undetectable levels of TNFRI whereas mature erythrocytes and platelets are uniformly negative for TNFRI expression. For the generation of the MABTNFR1-B1 hybridoma, BALB/c mice were immunized with purified, full-length human TNFRI protein that was expressed by insect cells that were infected with a recombinant human TNFRI-baculovirus expression vector. MABTNFR1-B1 specifically binds to natural and recombinant truncated forms of TNFRI.

Specifications

• Antigen: CD120a
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: TNF Receptor Type I
• Host Species: Mouse
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: MABTNFR1-B1
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.