anti-Caspase 10 Polyclonal, Thermo Scientific™

Caspase 10 Polyclonal antibody PA1-12507 from Thermo Scientific™ specifically detects Caspase 10 in Human, Mouse and Rat samples, and it is validated for Western Blot

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-12507

CASPASE 10

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11525992

Quantity Price
1 £ 260.0 / 100µg
Estimated Shipment date
from Supplier 05-01-2017
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Description and Specification

Specification

Antigen Caspase 10
Applications Western Blotting
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Purified
Formulation 100μg purified antibody in PBS and 0.02% sodium azide
Gene Accession No. Q92851
Gene Alias ALPS2, FLICE2, MCH4
Gene Symbols CASP10
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Isotype IgG
Quantity 100μg
Species Reactivity Human, Mouse, Rat
Storage Requirements Avoid Freeze/Thaw Cycles
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 843

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Formulation: 100μg purified antibody in PBS and 0.02% sodium azide
Synonyms: ALPS2, FLICE2, MCH4
Uniprot Accession: Q92851
Entrez GeneID: 843
Gene Symbol: CASP10
A suggested positive control for this product is HeLa whole cell lysate.