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Caspase 10 Polyclonal Antibody, Invitrogen™

Caspase 10 Antibody, PA1-12507, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: Western Blot.

Brand:  Invitrogen PA112507

UNSPSC : 12352203

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11525992

  • £260.00 / 100µg


Estimated Shipment
23-10-2017
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Description

Description

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Formulation: 100μg purified antibody in PBS and 0.02% sodium azide
Synonyms: ALPS2, FLICE2, MCH4
Uniprot Accession: Q92851
Entrez GeneID: 843
Gene Symbol: CASP10
A suggested positive control for this product is HeLa whole cell lysate.
Specifications

Specifications

Caspase 10
Unconjugated
Q92851
ALPS2, FLICE2, MCH4
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Rat
Western Blot
100μg purified antibody in PBS and 0.02% sodium azide
Purified
CASP10
Synthetic peptide corresponding to residues 505-521 of human FLICE2.
100μg
Primary
843