centromere protein M, Mouse, Clone: 4C12-2C8, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant C22orf18.

Brand:  Abnova H00079019-M01.100ug

Product Code. 16164013

Description

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM

Sequence: MSVLRPLDKLPGLNTATILLVGTEDALLQQLADSMLKEDCASELKVHLAKSLPLPSSVNRPRIDLIVFVVNLHSKYSLQNTEESLRHVDASFFLGKVCFLATGAGRESHCSIHRHTVVKLAHTYQSPLLYCDLEVEGFRATMAQRLVRVLQICAGHVPGVSALNLLSLLRSSEGPSLEDL

Specifications

• Antigen: centromere protein M
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: BC000705
• Gene Symbols: CENPM
• Immunogen: C22orf18 (AAH00705, 1 a.a. ∼ 180 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody

• Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: 4C12-2C8
• Description: Mouse monoclonal antibody raised against a full length recombinant C22orf18.
• Gene: CENPM
• Gene Alias: C22orf18/CENP-M/MGC861/PANE1/bK250D10.2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 79019
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ