BRD4 Mouse anti-Human, Clone: 23476, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen 730007

Product Code. 12847512

Descrizione

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

Specifica

• Antigen: BRD4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Gene: BRD4
• Gene Alias: BRD4-NUT fusion oncoprotein, BRD4-NUT FUSION
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 23476
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunoprecipitation
• Clone: 23476
• Conjugate: Unconjugated
• Gene Accession No.: O60885
• Gene Symbols: BRD4
• Immunogen: 333-460 of 1362 of BRD4 Protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1