Invitrogen™ BOLL Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530808

Product Code. 13435317

Description

Recommended positive controls: NT2D1. Predicted reactivity: Mouse (95%), Rat (95%), Rhesus Monkey (100%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: BOLL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BOLL
• Gene Alias: 4930554P13Rik; 4930597B14Rik; bol, boule-like; bol, boule-like (Drosophila); Boll; BOULE; boule homolog, RNA binding protein; boule-like RNA binding protein; boule-like RNA-binding protein; protein boule-like; RGD1559527
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 66037, 75388
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8N9W6, Q924M5
• Gene Symbols: BOLL
• Immunogen: Recombinant protein encompassing a sequence within the center region of human BOLL. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG