BNIP3L Polyclonal Antibody, Invitrogen™

BNIP3L Antibody, PA1-12514, from Invitrogen™. Species Reactivity: Human; Applications: Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-12514

BNIP3L

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11585992

Quantity Price
1 £ 273.0 / 100µg
Estimated Shipment date
from Supplier 21-03-2017
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Description and Specification

Specification

Formulation 100μg purified antibody in PBS and 0.02% sodium azide
Gene ID (Entrez) 665
Antigen BNIP3L
Storage Requirements Avoid Freeze/Thaw Cycles
Cross Reactivity Human
Immunogen Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
Isotype IgG
Primary or Secondary Primary
Format Purified
Gene Accession No. O60238
Host Species Rabbit
Conjugate Unlabeled
Species Reactivity Human
Gene Alias BNIP3a, NIX
Gene Symbols BNIP3L
Applications Western Blotting
Quantity 100μg
Monoclonal or Polyclonal Polyclonal

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.
Host Species: Rabbit
Cross Reactivity: Human
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues 77-92 of human Bnip3L.
Formulation: 100μg purified antibody in PBS and 0.02% sodium azide
Synonyms: BNIP3a, NIX
Uniprot Accession: O60238
Entrez GeneID: 665
Gene Symbol: BNIP3L
A suggested positive control for this product is K562 cell lysate.