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Description
B cell activation is initiated by crosslinking the B cell receptor, which leads to activation of non-receptor protein tyrosine kinases (PTK), including Btk, Syk, and three Src kinases, Fyn, Lyn, and Blk. Activated PTKs then phosphorylate multiple cellular proteins involved in B lymphocyte signaling. Syk is responsible for the tyrosine phosphorylation of B cell l i g 2, leading to the activation of downstream signaling pathways.
The J117-1278 monoclonal antibody recognizes the phosphorylated Y84 of BLNK.
Specifications
| BLNK (pY84) | |
| Monoclonal | |
| Alexa Fluor 647 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| J117-1278 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Phosphorylated Human BLNK Peptide | |
| 50 Tests | |
| Cell Biology | |
| Human, Mouse | |
| IgG2b κ |
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