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Invitrogen™ Beclin 1 Polyclonal Antibody

Product Code. 11565403
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Quantity:
100 μL
Unit Size:
100µL
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11565403 100 μL 100µL
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Product Code. 11565403 Supplier Invitrogen™ Supplier No. PA116857

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356.44 GBP valid until 2026-03-27
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Description

Rabbit Polyclonal Antibody

The target sequence has 88% sequence homology with rat. Suggested positive control: antigen standard for BECN1 (transient overexpression lysate).

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Beclin 1
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide; pH 7.4
Gene BECN1
Gene Accession No. O88597, Q14457, Q91XJ1
Gene Alias 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Gene Symbols BECN1
Host Species Rabbit
Immunogen Internal synthetic peptide to human Beclin 1, within residues 1-100.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114558, 56208, 8678
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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