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Invitrogen™ Beclin 1 Polyclonal Antibody

Product Code. 11591952
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Quantity:
100 μL
Unit Size:
100µL
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11591952 100 μL 100µL
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Product Code. 11591952 Supplier Invitrogen™ Supplier No. PA118287

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Description

Rabbit Polyclonal Antibody

PA1-18287 detects Beclin-1 from human samples. PA1-18287 has been successfully used in immunohistochemistry and immunofluorescence procedures. The PA1-18287 immunogen is a synthetic peptide corresponding to the C-terminal residues of human Beclin-1, conjugated to Blue Carrier Protein. The sequence is 100% conserved in mouse and rat. Reconstitute with 100 μL of distilled water.

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Beclin 1
Applications Immunohistochemistry (Frozen)
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with no preservative
Gene BECN1
Gene Accession No. Q14457
Gene Alias 4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Gene Symbols BECN1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the C-terminal residues of human Beclin-1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8678
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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