BDNF Polyclonal Antibody, Invitrogen™

BDNF Antibody, PA1-18371, from Invitrogen™. Species Reactivity: Human, Rat; Applications: ELISA, Immunohistochemistry, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-18371

BDNF

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 1.24740kg



Product Code. 11592012

Quantity Price
1 £ 303.0 / 100µL
Estimated Shipment date
from Supplier 22-03-2017
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Description and Specification

Specification

Formulation 100μL unpurified antibody in whole serum and no preservative
Applications Enzyme Linked Immunosorbent Assay
Applications Immunohistochemistry
Applications Western Blot
Antigen BDNF
Storage Requirements Avoid Freeze/Thaw Cycles
Cross Reactivity Human
Cross Reactivity Rat
Immunogen Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
Isotype IgG
Primary or Secondary Primary
Format Serum
Gene Accession No. P23363, P23560
Host Species Rabbit
Species Reactivity Human, Rat
Conjugate Unlabeled
Gene Alias Brain-derived neurotrophic factor, Abrineurin
Gene Symbols BDNF
Quantity 100μL
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 24225, 627

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Host Species: Rabbit
Cross Reactivity: Human, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: Brain-derived neurotrophic factor, Abrineurin
Uniprot Accession: P23363, P23560
Entrez GeneID: 24225, 627
Gene Symbol: BDNF
PA1-18371 detects BDNF from human and rat samples. PA1-18371 has been successfully used in immunohistochemistry, ELISA, and Western blot procedures. The PA1-18371 immunogen is a synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF, conjugated to KLH. After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. Reconstitute with 100 ul of distilled water.