missing translation for 'onlineSavingsMsg'
Learn More

BDNF Polyclonal Antibody, Invitrogen™

BDNF Antibody, PA1-18371, from Invitrogen™. Species Reactivity: Human, Rat; Applications: ELISA, Immunohistochemistry, Western Blot.

Brand:  Invitrogen PA118371

UNSPSC : 12352203

Code : LD

Additional Details : Weight : 1.24740kg

Product Code. 11592012

  • £303.00 / 100µL


Estimated Shipment
12-07-2017
Add to basket

Specifications

Description

BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Host Species: Rabbit
Cross Reactivity: Human, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: Brain-derived neurotrophic factor, Abrineurin
Uniprot Accession: P23363, P23560
Entrez GeneID: 24225, 627
Gene Symbol: BDNF
PA1-18371 detects BDNF from human and rat samples. PA1-18371 has been successfully used in immunohistochemistry, ELISA, and Western blot procedures. The PA1-18371 immunogen is a synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF, conjugated to KLH. After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles. Reconstitute with 100 ul of distilled water.
Description & Specifications

Specifications

BDNF
Unlabeled
P23363, P23560
Brain-derived neurotrophic factor, Abrineurin
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Rat
Western Blot
100μL unpurified antibody in whole serum and no preservative
Serum
BDNF
Synthetic peptide corresponding to residues H(131) S D P A R R G E L(140) of mouse BDNF.
100μL
Primary
24225, 627