Invitrogen™ APOE Monoclonal Antibody (4E4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA518068

Product Code. 15324341

Description

This antibody is specific for Apolipoprotein E4 and shows no cross-reactivity with ApoE2 or ApoE3.

Apo E (Apolipoprotein E) plays an important role in the metabolism of lipids in the plasma, and is also is a constituent of various plasma lipoprotein-lipid particles. The protein is synthesized in liver, brain, spleen, and the kidney, and concentrations are high in interstitial fluids, where it plays a role in distributing cholesterol from cells where cholesterol is in excess to cells which require cholesterol. Apo E also plays an important role in the formation of very low density lipoprotein and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13. 2.

Specifications

• Antigen: APOE
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P02649
• Gene Symbols: APOE
• Immunogen: Synthetic peptide corresponding to Human Apolipoprotein E4 conjugated to Keyhole Limpet Haemocyanin (KLH) (Immunogen sequence: ApoE4 peptide).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Dot Blot, ELISA, Immunoprecipitation, Western Blot, Western Blot
• Clone: 4E4
• Conjugate: Unconjugated
• Gene: APOE
• Gene Alias: AD2; AI255918; APOE; apo-E; ApoE4; APOEA; Apolipoprotein; apolipoprotein E; apolipoprotein E3; apolipoprotein E4; Apoprotein; B2G1; BG; LDLCQ5; LPG; MGC1571
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 348
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid