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Invitrogen™ AMPK gamma-1,2,3 Polyclonal Antibody

Product Code. 15517621
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Quantity:
100 μL
Unit Size:
100µL
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15517621 100 μL 100µL
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Product Code. 15517621 Supplier Invitrogen™ Supplier No. PA536314

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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 38, 54 and 63 kDa. Purity is >95% by SDS-PAGE.

The 5-AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non fermentor) kinase family, is a heterotrimeric protein comprise of alpha (63 kDa), beta (30 kDa) and gamma (38 kDa) subunits. The alpha subunit is the catalytic subunit, while beta and gamma are non catalytic subunits (although they have been found to interact with the active subunit in liver). AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase. AMPK is activated by AMP and can be also regulated by treatment with purified protein phosphatase in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMPK gamma-1,2,3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PRKAG1
Gene Accession No. O54950, P54619, P80385, Q8BGM7, Q91WG5, Q9UGI9, Q9UGJ0
Gene Alias 2410051C13Rik; 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase subunit gamma-2; 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-1 subunit; 5-AMP-activated protein kinase, gamma-2 subunit; 5'-AMP-activated protein kinase, gamma-3 subunit; AA571379; AAKG; AAKG2; adenosine monophosphate-activated protein kinase gamma 2-subunit; AI854673; Amkg3; AMP-activated protein kinase gamma 3 subunit; AMP-activated protein kinase gamma subunit; AMP-activated protein kinase gamma2 subunit; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma 2; AMPK gamma1; AMPK- gamma1; AMPK gamma-1 chain; AMPK gamma2; AMPK- gamma2; AMPK gamma-2 chain; AMPK gamma3; AMPK- gamma3; AMPK gamma-3 chain; AMPK subunit gamma-1; AMPK subunit gamma-2; AMPK subunit gamma-3; AMPKg; Ampkg3; AMPKg3L; AMPKg3S; BB036179; CMH6; H91620p; Prkaac; Prkag1; PRKAG2; PRKAG3; Prkga1; Protein kinase AMP-activated gamma; protein kinase AMP-activated non-catalytic subunit gamma 1; protein kinase AMP-activated non-catalytic subunit gamma 2; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 1 non-catalytic subunit; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catatlytic subunit; WPWS
Gene Symbols PRKAG1, PRKAG2, PRKAG3
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 50-100 of human AMPK gamma1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108099, 19082, 241113, 25520, 301518, 373545, 51422, 53632, 5571
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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